Making sense of microarray data to classify cancer
نویسندگان
چکیده
منابع مشابه
Making sense of microarray data distributions
MOTIVATION Typical analysis of microarray data has focused on spot by spot comparisons within a single organism. Less analysis has been done on the comparison of the entire distribution of spot intensities between experiments and between organisms. RESULTS Here we show that mRNA transcription data from a wide range of organisms and measured with a range of experimental platforms show close ag...
متن کاملMaking sense of cancer genomic data.
High-throughput tools for nucleic acid characterization now provide the means to conduct comprehensive analyses of all somatic alterations in the cancer genomes. Both large-scale and focused efforts have identified new targets of translational potential. The deluge of information that emerges from these genome-scale investigations has stimulated a parallel development of new analytical framewor...
متن کاملPdmclass Function to Classify Microarray Data Using Penalized Discriminant Methods
Description This function is used to classify microarray data. Since the underlying model fit is based on penalized discriminant methods, there is no need for a pre-filtering step to reduce the number of genes. Usage pdmClass(formula , method = c("pls", "pcr", "ridge"), keep.fitted = Arguments formula A symbolic description of the model to be fit. Details given below. method One of "pls", "pcr"...
متن کاملLearning Pathway-based Decision Rules to Classify Microarray Cancer Samples
Despite recent advances in DNA chip technology current microarray gene expression studies are still affected by high noise levels, small sample sizes and large numbers of uninformative genes. Combining microarray data with cellular pathway data by using new integrative analysis methods could help to alleviate some of these problems and provide new biological insights. We present a method for le...
متن کاملMaking sense of cancer.
Nurses caring for patients with cancer do so at varying stages of the disease trajectory from diagnosis to death. Having an understanding of cancer biology, potential causes and classification should enable you to understand the treatment options and to communicate more effectively with patients, their families and friends.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The Pharmacogenomics Journal
سال: 2003
ISSN: 1470-269X,1473-1150
DOI: 10.1038/sj.tpj.6500209